Jane Geisler-Lee Research Professor   Ph.D. 2002, The Ohio State University   Bioinformatics, Cell Biology, Cell Wall Biology, Metabolism   Office: Life Science II room 483 Lab: Life Science II 403 (shared with  M. Geisler) Office: 618-453-6460 email:

Research Interests

Complex metabolism and its regulation puzzle me.  I have been using suberin biosynthesis as a model pathway and as a first step to develop methods towards the global understanding of metabolism.  Different bioinformatic, computational and experimental approaches have been used in parallel in Arabidopsis.  My research aims are to reconstruct the biosynthetic and regulatory pathway(s) of suberin and to apply this approach to other metabolic pathways.  This reconstruction will greatly enhance the practical use of suberin as a renewable bio-polymer and also help in the design of other bio-polymers for industrial applications.  A global understanding of metabolic regulation will advance our ability to perform metabolic engineering.   

Selected Publications

1. Schuette, S., A.J. Wood, M. Geisler, J. Geisler-Lee, R. Ligrone, and K.S. Renzaglia. Accepted. Novel localization of callose in Physcomitrella patens and phylogenomic analysis of the callose synthase gene family.  Annals of Botany.
2. Gallie, D.R., J. Geisler-Lee, J. Chen and B. Jolley. In press.  Tissue-specific expression of the ethylene biosynthetic machinery regulates root growth in maize. Plant Molecular Biology. Link to pdf file HERE.
3. Geisler-Lee, J., N. O'Toole, R. Ammar, N.J. Provart, A.H. Millar, and M. Geisler. 2007. A predicted interactome for Arabidopsis thaliana. Plant Physiology 145: 317-329.  Link to pdf file HERE.
   
4. Ross, D, A. G. Ivanov, A. Fu, J. Geisler-Lee, L. Hendrickson, M. Geisler, G. Stewart, M. Krol, S. R. Rodermel, D. P. Maxwell, and N. P. Huner. 2006. IMMUTANS does not act as a stress-induced safety valve in the protection of the photosynthetic apparatus of Arabidopsis during steady-state photosynthesis. Plant Physiology 142:574-585.
5. Geisler-Lee, J., M. Geisler, P. Coutinho, B. Segerman, N. Nishikubo, J. Takahashi, H. Aspenborg, S. Djerbi, E. Masters, S. Andersson-Gunner, B. Sundberg, S. Karpinski, T. Teeri, L. Kleczkowski, B. Henrissat, and E. Mellerowicz. 2006.  Poplar carbohydrate active enzymes (CAZymes). Gene identification and expression analyses.  Plant Physiology 140:946-962. Link to pdf file HERE.

SIUC / College of Science / Plant Biology
URL: http://www.science.siu.edu/plant-biology/Adjunct/Lee.bio.html
Last updated: 19-Nov-08 / dln